People
Ms LAM Ling Ning, Kaylie
PhD Student

Supervisor/PI: Asst Prof. Kimberly Kline

Project title: Characterisation of E. faecalis biofilm in an iron-enriched environment

Research Interest

My research focus is on understanding the role of iron in Enterococcus faecalis biofilm physiology. In general, iron is essential for biological processes. To date, we have discovered that E. faecalis biofilm utilise ferric iron-mediated extracellular electron transfer (EET), allowing a metabolic shift toward greater energy production and growth. Moreover, we are now looking into the role of endocarditis- and biofilm-associated pilus (ebp) and cation efflux transporter in iron-mediated biofilm augmentation. Further on-going studies to understand the role of EET will answer in what way this mechanism could potentially play a role in virulence and pathogenesis.