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Biofilm Biology
Unravelling the mechanisms behind biofilm establishment, development, structure and function to understand and control key aspects of biofilm biology in all settings, including natural and engineered urban environments, host-microbe interactions, public health and medical contexts.
Environmental Engineering
Understanding microbial communities in engineered and environmental settings and provide translational outcomes for harnessing of biochemical transformation processes in several key systems.
Integrative Analysis Unit
The Integrative Analysis Unit (IAU) provides analysis and interpretation expertise, guiding and advising SCELSE researchers on metagenome analysis and related methods, as well as experimental design, data analysis and statistics.
Meta-'omics & Microbiomes
The development and application of cutting edge, high resolution, ‘omics, and analytical technologies to understand microbial communities and microbiomes in natural or engineered systems to the level where informed control can be applied.

Interdisciplinary research

Effective interdisciplinary research is critical to the future of innovative scientific enquiry and its application to urgent practical problems. SCELSE has assembled a multidisciplinary team of world-class researchers from diverse but complementary fields, uniquely providing a coherent research environment that fosters interdisciplinary teamwork.  

SCELSE's three multidisciplinary research clusters work together to unravel the science of microbial biofilm communities, the understanding of which has relevance for all ecosystems and habitats. The top-down (Meta-'omics & Microbiomes) and bottom-up (Biofilm Biology) clusters are guided by the output of the Environmental Engineering cluster, which in turn, contributes postanalysis input into these groups. All clusters are supported by the Integrative Analysis Unit for analysis and interpretation of large data sets arising from the centre’s high throughput sequencing and metabolomics core facilities, experimental design, analysis and statistics.

This iterative approach revolves around comprehensive data collection and in-depth mechanistic analyses of microbial biofilm communities. The outcomes of these are used to develop diagnostic and predictive tools for validation of the new biological understanding.

Research Capacities

Our understanding of biofilms is rapidly unfolding with the advent of sophisticated technologies, including SCELSE's state-of-the-art facilities.

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Research Themes

SCELSE has eight core research themes, many of which are integrated across multiple research clusters and highlight the interdisciplinary nature of the centre’s research. These themes deliver biological insights and concepts, and identify commonalities applicable to any ecosystem, as well as generate specific knowledge for translational outcomes.

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Collaborative Research

Community-driven processes for environmentally sustainable outcomes. Research undertaken at SCELSE will elucidate the biology of microbial biofilms.

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