Wastewater surveillance of SARS-CoV-2 across 40 US states from February to June 2020
Reference: Water Research (2921) 202: 117400

Wastewater-based disease surveillance is a promising approach for monitoring community outbreaks. Here we describe a nationwide campaign to monitor SARS-CoV-2 in the wastewater of 159 counties in 40 US states, covering 13% of the US population from February 18 to June 2, 2020. Out of 1,751 total samples analysed, 846 samples were positive for SARS-CoV-2 RNA, with overall viral concentrations declining from April to May. Wastewater viral titers were consistent with, and appeared to precede, clinical COVID-19 surveillance indicators, including daily new cases. Wastewater surveillance had a high detection rate (>80%) of SARS-CoV-2 when the daily incidence exceeded 13 per 100,000 people. Detection rates were positively associated with wastewater treatment plant catchment size. To our knowledge, this work represents the largest-scale wastewater-based SARS-CoV-2 monitoring campaign to date, encompassing a wide diversity of wastewater treatment facilities and geographic locations. Our findings demonstrate that a national wastewater-based approach to disease surveillance may be feasible and effective.

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Published By
Wu F., Xiao A., Zhang J., Moniz K., Endo N., Armas F., Bushman M., Chai P.R., Duvallet C., Erickson T.B., Foppe K., Ghaeli N., Gu X., Hanage W.P., Huang K.H., Lee, W.L., McElroy K.A., Rhode S.F., Wuertz S., Janelle THOMPSON, S.