News & Events
Surface sensing during the first 20 generations of bacterial life on a surface
Speaker(s): Prof. Gerard Wong (Dept. of Chemistry & Biochemistry University of California, Los Angeles, USA)
When: 14 July 2016 (2:40 - 3:20pm)
Where: Experimental Medicine Building, Learning Studio (Level 1), Nanyang Technological University, Singapore
Type: Biophysics of Biofilms Symposium

Bacterial biofilms are integrated communities of cells that adhere to surfaces and are fundamental to the ecology and biology of bacteria. The accommodation of a free-swimming cell to a solid surface is more complex than passive cell adhesion. We started a multi-disciplinary study to investigate the interplay between motility appendages, molecular motors, exopolysaccharide production, and hydrodynamics near the surface environment using state of the art tools from different fields that are not usually combined, including theoretical physics, community tracking with single cell resolution, genetics, and microbiology. We explore theme such as surface sensing and its relation to multi-generational signaling via secondary messengers and precise downstream motility consequences, and the subsequent onset of microcolony organisation via interactions between appendages and exopolysaccharides.