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Singapore International Summer Camp 2 - 6 June 2026

Calling teens keen on science, tech & business! Here’s your chance to stay at NTU for 5N and gain hands-on exposure to microbiome research, sustainability and entrepreneurship.

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How bacteria suppress immune defences in stubborn wound infections

SCELSE, SMART and UNIGE scientists found that Enterococcus faecalis releases lactic acid that weakens immune cells, helping infections persist. This discovery may lead to new ways to treat chronic wounds.

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SCELSE wins Silver at NTU Safety & Health Awards 2025

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UNIGE and NTU Singapore scientists find that silencing bacteria can worsen heart infections

In infectious disease research, disrupting bacterial communication is widely considered beneficial. A study by UNIGE and NTU Singapore shows this is not always true.

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Who we are

SCELSE (pronounced “cell-see”) is a leading multidisciplinary biofilm and microbiome research centre and a distinguished Research Centre of Excellence. SCELSE advances sustainability and translational impact through cutting-edge research and innovative solutions, driving progress in:

  • Healthcare
  • Industry
  • Society
  • Environment
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SCELSE’s Research Structure

Mission: “To discover, control and direct the behaviour of microbial biofilm communities and microbiomes for sustainable environmental, engineering, public health and medical applications.”

Environmental Engineering Cluster

Research in Environmental Engineering focuses on microbiomes in the urban water cycle, pollutant degradation, wastewater, nutrient removal, resource recovery and technologies for a circular bioeconomy.

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Biofilm Biology Cluster

SCELSE uses a multidisciplinary approach to understand the fundamental aspects of biofilm structure and function, studying how microbial interactions and the extracellular polymeric matrix impart the emergent properties that enable biofilm success.

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Meta-‘omics & Microbiomes Cluster

The Meta-'omics & Microbiomes cluster uses a top-down approach to identify microbiome and biofilm members, their functions, and community responses to novel and changing environments.

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Biofilms & Health Cluster

The Biofilms & Health cluster addresses public health and medical issues, focusing on prevention and treatment of biofilm infections and the development of sustainable antimicrobial technologies.

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Integrative Analysis Unit

The Integrative Analysis Unit addresses the need to comprehend the complexity of downstream analysis of metagenome and metatranscriptome datasets, ensure robust experimental design, to maximise data utilisation, and research output.

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    Latest Scientific Publications

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