News & Events
Surface sensing, motility appendages, and hydrodynamics in bacterial interactions with surfaces
Speaker(s): Prof. Gerard Wong, Department of Bioengineering, Department of Chemistry & Biochemistry, California NanoSystems Institute, University of California, Los Angeles (UCLA)
When: 12 July 2017 (3:00 - 4:00pm)
Where: Experimental Medicine Building (EMB) Seminar Room 1 (Level 1)
Type: Seminars

Abstract

Bacterial biofilms are integrated communities of cells that adhere to surfaces and are fundamental to the ecology and biology of bacteria. The accommodation of a free-swimming cell to a solid surface is more complex than simply modulation of cell adhesion. We investigate the interplay between motility appendages, molecular motors, hydrodynamics, and exopolysaccharide production near the surface environment using state of the art tools from different fields that are not usually combined, including theoretical physics, community tracking with single cell resolution, genetics, and microbiology. Themes such as surface sensing, multi-generational signaling via secondary messengers, subsequent downstream motility consequences, and the subsequent onset of microcolony organisation via interactions between appendages and exopolysaccharides will be discussed.

Biography

Gerard C. L. Wong is a Professor in the Department of Bioengineering, Department of Chemistry, and the California NanoSystems Institute at UCLA.  Wong received his BS and PhD at Caltech physics and Berkeley physics respectively. He joined the Materials Science & Engineering Dept and Physics Dept at the University of Illinois at Urbana-Champaign in 2000 and moved to UCLA in 2009. His research recognition includes: the Beckman Young Investigator Award, Alfred P Sloan Fellowship, and Sackler Distinguished Speaker. He is a Fellow of the American Physical Society (2011), and a Fellow of the American Academy of Microbiology (2016). His current research interests include bacterial biofilms, innate immunity, and antibiotic design.