Discovery of cephalosporin-3_-diazeniumdiolates that show dual antibacterial and antibiofilm effects against Pseudomonas aeruginosa clinical cystic fibrosis isolates and efficacy in a murine respiratory infection model

Author(s): Rineh, Ardeshir,Soren, Odel,McEwan, Timothy,Ravikumar, Vikashini,Poh, Wee Han,Azamifar, Fereshteh,Naimi-Jamal, M. Reza,Cheung, Chen-Yi,Elliott, Alysha G.,Zuegg, Johannes,Blaskovich, Mark A. T.,Cooper, Matthew A.,Dolange, Victoria,Christodoulides, Myron,Cook, Gregory M.,Rice, Scott A.,Faust, Saul N.,Webb, Jeremy S. and Kelso, Michael J.

Reference: ACS Infectious Diseases (2020), 6: 1460-1479

Research Cluster(s): Biofilm Biology Cluster

Theme(s): Biofilm Detection & ControlBiofilm Detection & Control