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In-vitro and in-vivo efficacy of LpxC inhibitor, CHIR-090, alone or combined with colistin against Pseudomonas aeruginosa biofilm

In-vitro and in-vivo efficacy of LpxC inhibitor, CHIR-090, alone or combined with colistin against Pseudomonas aeruginosa biofilm

Author(s): Tan, Jun Hou,Vidaillac, Celine,Yam, Joey Kuok Hoong,Chua, Song Lin,Givskov, Michael and Yang, Liang
Reference: Antimicrobial Agents and Chemotherapy (2017), 61: e02223-16
Research Cluster(s): Biofilm Biology Cluster