Unveiling Biofilm Secrets Using Microcalorimetry

Abstract:
Microcalorimetry emerges as a groundbreaking tool in biofilm research, revolutionizing the study of microbial survival and metabolism within intricate biofilm structures. Unlike traditional methods, microcalorimetry allows researchers to detect and analyse cells in situ, even in the deepest layers of a biofilm, eliminating the need for disruptive removal procedures.

This innovative technology operates by detecting minute amounts of metabolic heat, offering unparalleled sensitivity. Its applicability extends to turbid media, complex models, and intricate samples, providing researchers with a comprehensive understanding of biofilm dynamics. Microcalorimetry delivers real-time metabolic output data, enabling continuous monitoring of biofilm behaviour. Additionally, it provides valuable kinetic data for treatments, empowering researchers with insights into the efficacy and temporal aspects of interventions. In essence, microcalorimetry represents a cutting-edge solution for in-depth, non-invasive biofilm analysis, offering a new frontier in the exploration of microbial communities.

Speaker:
Dr Madle Sirel
Application and Product Support Manager, Symcel

Biography:
Dr Madle Sirel is an accomplished scientist with a PhD in Infection Biology and Cell Biology from Karolinska Institute, where she specialized in the intricate interactions between pathogens and host. For the past three years, she has been at the forefront of innovative research at Symcel, where she has specialized in the application of microcalorimetry across various research domains.